{"created":"2024-03-04T07:15:52.608832+00:00","id":2009067,"links":{},"metadata":{"_buckets":{"deposit":"b5bb6ce1-18ea-4a0a-9015-e5e85da18f0d"},"_deposit":{"created_by":9,"id":"2009067","owners":[9],"pid":{"revision_id":0,"type":"depid","value":"2009067"},"status":"published"},"_oai":{"id":"oai:our.repo.nii.ac.jp:02009067","sets":["1707963525245","1707979148924:1707983962284"]},"author_link":[],"item_30002_access_rights4":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_30002_creator2":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"田代, 隆良","creatorNameLang":"ja"},{"creatorName":"タシロ, タカヨシ","creatorNameLang":"ja-Kana"},{"creatorName":"Tashiro, Takayoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"後藤, 純","creatorNameLang":"ja"},{"creatorName":"ゴトウ, ジュン","creatorNameLang":"ja-Kana"},{"creatorName":"Goto, Jun","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"重野, 秀明","creatorNameLang":"ja"},{"creatorName":"シゲノ, ヒデアキ","creatorNameLang":"ja-Kana"},{"creatorName":"Shigeno, Hideaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"後藤, 陽一郎","creatorNameLang":"ja"},{"creatorName":"ゴトウ, ヨウイチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Goto, Yoichiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"黒田, 芳信","creatorNameLang":"ja"},{"creatorName":"クロダ, ヨシノブ","creatorNameLang":"ja-Kana"},{"creatorName":"Kuroda, Yoshinobu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"那須, 勝","creatorNameLang":"ja"},{"creatorName":"ナス, マサル","creatorNameLang":"ja-Kana"},{"creatorName":"Nasu, Masaru","creatorNameLang":"en"}]}]},"item_30002_date11":{"attribute_name":"Date","attribute_value_mlt":[{"subitem_date_issued_datetime":"1988-02-20","subitem_date_issued_type":"Issued"}]},"item_30002_description9":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"原発性肺癌患者56例の血清CA19-9濃度を測定した.初診時・治療前の陽性率は16%, 経過中最高値をとっても30%とCEAにくらべ低かった.血清濃度は腺癌とくに気管支腺型腺癌で著増し, 免疫組織化学的にも大量のCA19-9の局在が認められた.しかし、血清濃度と組織内局在とは必ずしも相関せず, 腫瘍の大きさや血管浸潤などが関与しているものと思われた。 The 19-9 monoclonal antibody, prepared by Koprowski et al., reacts with a carbohydrate antigenic determinant (CA 19-9) which has been identified as a sialylated lacto-N-fucopentaose II. CA19-9 has been known to be a useful tumor marker for gastrointestinal carcinoma, especially pancreatic cancer. The authors investigated the significance of this antigen for lung cancer. We measured serum CA 19-9 concentration in 56 patients with lung cancer by a forward sandwich type radioimmunometric assay (cut-off value 37 U/ml), and immunostained the antigen in 32 lung cancer tissue by an immunoperoxidase assay. The positive rate of serum CA 19-9 concentration was 16%, lower than that of carcinoembryonic antigen (CEA). The concentration of the antigen was markedly increased in patients with bronchial gland type adenocarcinoma, and strongly stained in cancer tissue.","subitem_description_language":"ja"}]},"item_30002_file35":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2010-01-04"}],"filename":"haigan_28_1.pdf","format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://our.repo.nii.ac.jp/record/2009067/files/haigan_28_1.pdf"},"version_id":"7f2a4ea0-d9a0-434a-b2c9-c2b4a76d5b01"}]},"item_30002_identifier16":{"attribute_name":"Identifier","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/10559/14665"}]},"item_30002_issue_number25":{"attribute_name":"Issue Number","attribute_value_mlt":[{"subitem_issue":"1"}]},"item_30002_language12":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_30002_page_end28":{"attribute_name":"Page End","attribute_value_mlt":[{"subitem_end_page":"17"}]},"item_30002_page_start27":{"attribute_name":"Page Start","attribute_value_mlt":[{"subitem_start_page":"11"}]},"item_30002_publisher10":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"日本肺癌学会","subitem_publisher_language":"ja"}]},"item_30002_relation18":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"AN00203978","subitem_relation_type_select":"NCID"}}]},"item_30002_resource_type13":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_30002_rights6":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"本文データは日本肺癌学会の許諾に基づきCiNiiから複製したものである","subitem_rights_language":"ja"}]},"item_30002_source_identifier22":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"03869628","subitem_source_identifier_type":"ISSN"}]},"item_30002_source_title23":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_source_title":"肺癌","subitem_source_title_language":"ja"}]},"item_30002_subject8":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Tumor marker","subitem_subject_language":"en"},{"subitem_subject":"Carbohydrate Antigen(CA)19-9","subitem_subject_language":"en"},{"subitem_subject":"Lung cancer","subitem_subject_language":"en"}]},"item_30002_title0":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"原発性肺癌におけるCA19-9の意義 : 血中濃度と組織内局在の検討","subitem_title_language":"ja"},{"subitem_title":"The Carbohydrate Antigen 19-9 in Serum and Tissue of Patients with Lung Cancer","subitem_title_language":"en"}]},"item_30002_volume_number24":{"attribute_name":"Volume Number","attribute_value_mlt":[{"subitem_volume":"28"}]},"item_title":"原発性肺癌におけるCA19-9の意義 : 血中濃度と組織内局在の検討","item_type_id":"30002","owner":"9","path":["1707963525245","1707983962284"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-01-04"},"publish_date":"2010-01-04","publish_status":"0","recid":"2009067","relation_version_is_last":true,"title":["原発性肺癌におけるCA19-9の意義 : 血中濃度と組織内局在の検討"],"weko_creator_id":"9","weko_shared_id":-1},"updated":"2024-03-19T01:20:07.822324+00:00"}