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正常成人肛門管における生理的18F-FDG取り込み:PET/CTによる評価
http://hdl.handle.net/10559/17158
http://hdl.handle.net/10559/17158569652f9-5f74-468c-a484-f232408a587f
| Item type | デフォルトアイテムタイプ（フル）(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-04-06 | |||||||||
| タイトル | ||||||||||
| タイトル | Physiological 18F-FDG uptake in the normal adult anal canal: evaluation by PET/CT | |||||||||
| 言語 | en | |||||||||
| タイトル | ||||||||||
| タイトル | 正常成人肛門管における生理的18F-FDG取り込み:PET/CTによる評価 | |||||||||
| 言語 | ja | |||||||||
| 作成者 |
Sena Sanches, Yankel Carolina
× Sena Sanches, Yankel Carolina
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| アクセス権 | ||||||||||
| アクセス権 | metadata only access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||
| 内容記述 | ||||||||||
| 内容記述 | Objective: Despite their benefit for detecting primary tumors, data for normal 18F-fluoro-2-deoxy-D-glucose (FDG) uptake in the anal canal are insufficient. Here we used positron emission tomography-computed tomography (PET/CT) to determine the uptake of FDG in the normal adult anal canal (AC) and to evaluate its clinical significance compared with that of anal cancer. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述 | Methods: We conducted a retrospective study of-PET/CT images in the anal region, of 201 consecutive patients without symptoms or pathology taken from January 2015 to August 2019, after excluding two patients (one each with Crohn's disease and hemorrhoid). These patients were included in the normal group, and data of eight patients with anal cancer were collected from January 2011 to August 2019 for comparison. FDG uptake was quantitatively evaluated (compared with the maximum standardized uptake value [SUVmax] to the SUVmax values of liver and distal rectum) and qualitatively (compared with background) in early and delayed phases. Normal grade 3 uptake was qualitatively defined as FDG uptake higher than the surrounding muscles. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述 | Results: In the normal group, mean anal canal SUVmax of early phase was: 2.26 (range 1.00-6.30), and delayed phase: 2.52 (range 1.00-8.80). Their ratios to liver SUVmax were early: 0.74 (range 0.24-2.25), and delayed: 0.81 (range 0.23-2.32); ratios to rectal SUVmax were early: 0.87 (range 0.30-1.89), and delayed: 0.90 (range 0.30-1.27). Qualitatively, 25 patients (15.4%) had normal grade 3 uptake during the early and delayed phases. In contrast, qualitative data showed that all patients with anal cancer exhibited high FDG uptake in the anal canal. The mean early- and delayed-phase values of SUVmax of the anal canal and anal cancer group were 11.09 (range 5.40-17.73) and 14.23 (range 6.70-22.85), respectively. There was a significant difference between the mean-early and -delayed anal SUVmax values of the normal grade 3 and anal cancer groups. Furthermore, the ratios to liver SUVmax were significantly different between the two groups. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述 | Conclusions: PET/CT scans occasionally showed high FDG uptake in the anal canal of healthy adults. Comparing the SUVmax values of liver FDG uptake may help differentiate between normal tissue and anal cancer. | |||||||||
| 言語 | en | |||||||||
| 出版者 | ||||||||||
| 出版者 | 大分大学 | |||||||||
| 言語 | ja | |||||||||
| 日付 | ||||||||||
| 日付 | 2023-01-01 | |||||||||
| 日付タイプ | Issued | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ | doctoral thesis | |||||||||
| 識別子 | ||||||||||
| 識別子 | http://hdl.handle.net/10559/17158 | |||||||||
| 識別子タイプ | HDL | |||||||||
| 関連情報 | ||||||||||
| 関連タイプ | isVersionOf | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1007/s12149-020-01480-9 | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 甲第699号 | |||||||||
| 学位名 | ||||||||||
| 言語 | ja | |||||||||
| 学位名 | 博士(医学) | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2023-03-23 | |||||||||
| 学位授与機関 | ||||||||||
| 言語 | ja | |||||||||
| 学位授与機関名 | 大分大学 | |||||||||
